| Aliquippa 42, Derry Area 19 |
| Archbishop Wood 57, Simon Gratz 6 |
| Berks Catholic 49, Milton Hershey 21 |
| Bethlehem Catholic 73, Saucon Valley 14 |
| Bethlehem Freedom 49, Emmaus 17 |
| Bishop McDevitt 40, Conrad Weiser 16 |
| Cathedral Prep 55, Clearfield Area 21 |
| Cocalico 61, William Penn (3) 35 |
| Conwell-Egan Catholic 28, North Schuylkill 14 |
| Harrisburg 16, Central Dauphin 6 |
| Hollidaysburg 31, Wallenpaupack 0 |
| Juniata Valley 9, Bishop Guilfoyle 3 |
| Lackawanna Trail 41, Tri-Valley 6 |
| Manheim Central 42, Cedar Cliff 20 |
| Middletown Area 42, Bermudian Springs 20 |
| Montoursville 32, Danville 0 |
| Our Lady of the Sacred Heart 28, Rochester 6 |
| Pine-Richland 34, Seneca Valley 7 |
| Richland Township 21, Ligonier Valley 12 |
| Saint Joseph’s Prep 49, Northeast 14 |
| Scranton Prep 47, Lakeland 19 |
| South Fayette 31, Thomas Jefferson 24 |
| Southern Columbia 39, Mount Carmel Area 14 |
| Upper Dublin 40, Unionville 7 |
| West Catholic 21, Dunmore 3 |
| West Chester Rustin 10, Penn Wood 8 |
| Wilmington Area 40, Chestnut Ridge 33 |