| Aliquippa 42, Beaver Falls 14 |
| Archbishop Wood 24, Archbishop Ryan 17 |
| Bald Eagle Area 21, Forest Hills 16 |
| Bedford 47, Westinghouse 16 |
| Berks Catholic 35, Lampeter-Strasburg 14 |
| Bermudian Springs 20, Lancaster Catholic 10 |
| Bishop McDevitt 49, West Perry 14 |
| Cathedral Prep 52, University Prep 8 |
| Cedar Cliff 33, Warwick 23 |
| Central Dauphin 27, Manheim Township 0 |
| Charleroi 42, Mohawk Area 13 |
| Chestnut Ridge 48, Everett 14 |
| Clearfield Area 49, Bellefonte 21 |
| Coatesville 38, Downingtown East 19 |
| Coudersport 22, Clarion-Limestone 12 |
| Derry Area 36, Cardinal Wuerl North Catholic 29 |
| Downingtown West 24, Harry S. Truman 22 |
| Freedom 7, Burgettstown 6 |
| Garnet Valley 49, Quakertown Community 14 |
| Gateway 35, Franklin Regional 0 |
| Hollidaysburg 33, Oil City 22 |
| Imhotep Charter School 46, John Bartram 8 |
| Manheim Central 51, Governor Mifflin 14 |
| Middletown Area 41, Wyomissing Area 6 |
| Milton Hershey 14, Susquehanna Township 6 |
| North Penn 13, Neshaminy 6 |
| Northern Cambria 36, Saltsburg 34 |
| Our Lady of the Sacred Heart 27, Clairton 7 |
| Penn Hills 34, McKeesport Area 7 |
| Peters Township 38, Penn-Trafford 35 |
| Pine-Richland 46, Mount Lebanon 16 |
| Pottsgrove 40, Pottstown Area 6 |
| Richland Township 59, Penns Valley 7 |
| Rochester 27, Jeannette 0 |
| Saint Joseph’s Prep 23, LaSalle College HS 13 |
| Seneca Valley 31, North Allegheny 14 |
| Smethport Area 28, Curwensville Area 0 |
| South Fayette 28, Belle Vernon Area 10 |
| South Side Area 32, Shady Side Academy 16 |
| State College Area 55, McDowell 20 |
| Steel Valley 39, Washington 7 |
| Thomas Jefferson 47, Blackhawk 7 |
| Unionville 28, Radnor 7 |
| Upper Dublin 27, Cheltenham 0 |
| West Allegheny 14, Woodland Hills 13 |
| William Penn (3) 22, Shippensburg Area 6 |
| Wilmington Area 50, Sharpsville 7 |
| York Catholic 28, Delone Catholic 21 OT |