| 10/6/18 |
| Bethlehem Catholic 41, East Stroudsburg South 28 |
| Emmaus 49, Allentown Central Catholic 14 |
| Notre Dame 49, Pen Argyl 10 |
| 10/5/18 |
| Bethlehem Freedom 35, Easton Area 7 |
| Jim Thorpe Area 14, Blue Mountain 0 |
| Marian Catholic 30, Panther Valley 6 |
| Minersville Area 26, Mahanoy Area 14 |
| Nazareth Area 26, Bethlehem Liberty 13 |
| Northern Lehigh 27, Salisbury Township 13 |
| Palisades 51, Bangor 13 |
| Palmerton Area 59, Catasauqua 14 |
| Parkland 49, Whitehall 21 |
| Pleasant Valley 21, East Stroudsburg North 18 |
| Pocono Mountain East 10, William Allen 9 |
| Pocono Mountain West 41, Louis E. Dieruff 14 |
| Pottsville Area 21, Lehighton 13 |
| Saucon Valley 49, Wilson Area 14 |
| Schuylkill Haven 51, Shenandoah Valley 0 |
| Southern Lehigh 45, Northwestern Lehigh 21 |
| Stroudsburg 34, Northampton 26 |
| Tamaqua Area 26, North Schuylkill 14 |
| Tri-Valley 63, Millersburg 34 |
| Williams Valley 21, Pine Grove Area 14 |